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10.1016/j.pbi.2017.03.011 182 LohanS
Cycling protocols help minimize copper accumulation concerns
Probucol's antioxidant effects make it a potential alternative therapy for improving atherosclerotic disease and effectively preventing carotid atherosclerosis progression in hypercholesterolemic patients ( 5.2.4 Ferroptosis suppressor protein 1 and coenzyme Q10 pathway FSP1 possesses NAD(P)H oxidoreductase activity and reduces CoQ to ubiquinol (CoQH2), which inhibits lipid peroxidation and ferroptosis by trapping lipid peroxidation free radicals ( Besides the FSP1-CoQ pathway, recent evidence has revealed an alternative ferroptosis defense mechanism involving dihydroorotate dehydrogenase (DHODH) and coenzyme Q10
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