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Whether one sees it as an ingenious case study in branding or an ethical misstep in consumer culture, the evolution of cigarette advertising serves as a rich lesson in how corporate interests, government policies, and cultural norms intersect

Consumer research in Japan revealed that the top two reasons for switching were not having to worry about unpleasant smells nor affecting others and also that they are less harmful than cigarettes

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This result was also confirmed in the rescue experiment, as a miRNA-218-5p inhibitor reduced the inhibition effect of MIR155HG on CSE-induced HPMECs

PMCID: PMC4154357