Common side effects The most frequently reported side effects are mild and transient: Dizziness (most common, usually related to injection speed) Headache (typically resolves within 24 hours) Skin flushing (related to vasodilation effects) Nausea (more common at higher doses) Fatigue or insomnia (varies by individual) Agitation or anxiety (infrequent) Weight loss (reported in some longer-term studies) Feeling hot (transient, related to administration) Most of these side effects correlate with administration speed rather than the compound itself
However, injection-based use carries important concerns, including sterility, contamination risk, uncertain dosing, and lack of regulatory oversight
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In addition, this combination not only inhibits inhibitor of nuclear factor kappa B (NF-B) phosphorylation, thereby reducing nuclear translocation of NF-B and suppressing downstream inflammatory cytokine expression (TNF- and ICAM-1 mRNA) within the NF-B signaling pathway but also mitigates phosphorylation of Janus Kinase 1 (JAK1) and signal transducer and activator of transcription 1 (STAT1), suppressing activation of the JAK1/STAT1 pathway to enhance inflammatory response inhibition post-cerebral ischemia
Its antioxidant properties help neutralize free radicals caused by intense physical activity, which can reduce soreness and accelerate muscle recovery
