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The study included both in vivo analysis from two phase 2 clinical trials and in vitro experiments using primary human hepatocytes

And theres one final piece of information in my arsenal the recent Guidelines on treating Cobalamin states that injections remain the most reliable method of treatment and that patients would prefer them as they are tried and tested

Brain Behav 11:e2408 Perin MT et al (2023) Homocysteine levels, genetic background, and cognitive impairment in Parkinsons disease