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PLoS One 2016

(History + Background) IGF-1 DES , or Insulin-like Growth Factor 1 DES(1-3) , is a modified version of IGF-1 a powerful anabolic growth factor that plays a critical role in: Muscle growth Tissue repair Recovery Cellular regeneration It is essentially a truncated form of native IGF-1: 13 amino acids shorter than full-length IGF-1 Lacks the first three N-terminal amino acids (hence the name DES(1-3) ) This structural modification gives IGF-1 DES two unique properties: Greatly increased receptor binding affinity 10x more potent locally vs

6.1.2 Liposomes Liposomes are nanovesicles composed of uni-lamellar or multilamellar phospholipid bilayers with a central aqueous core

Its designed for advanced models focused on cellular repair, inflammation response, and recovery signaling