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In addition to these metabolic and nutritional pathways, gut microbiota dysbiosis also influences neuroendocrine regulatory mechanisms through modulation of neurotransmitter synthesis

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The high local concentration is exactly what's needed to study the peptide's direct effects on the damaged intestinal wall

doi: 10.1038/sj.bjc.6602877 226 SuzukiSAkechiTKobayashiMTaniguchiKGotoKSasakiSet al