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Expert Opin Ther Pat 29(9):703731 Seddigi ZS et al (2017) Recent advances in combretastatin based derivatives and prodrugs as antimitotic agents

In the transgenic APPswePS1dE9 (APP/PS1) mouse model, which stimulates amyloidosis and gliosis, targeting reactive astrocytes improved cognitive function demonstrating their potential for treatment in AD 133

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