Additionally, BCS1L, TTC19, and UQCC2, encoded by nDNA, are involved in the assembly of complex III ( Mutations in cytochrome b can manifest in skeletal muscle involvement, exercise intolerance, MELAS, LS, and seizures ( BCS1L mutations are the most common cause of complex III deficiency and are linked to GRACILE syndrome, Bjrstand syndrome, liver disease, encephalopathy, dyskinesia, and epilepsy
Although these approaches are still in experimental stages, they could potentially correct underlying genetic abnormalities or promote neural regeneration
Taking biotin with food is generally recommended, especially for higher doses
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