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Description

10.1146/annurev.bi.55.070186.004405 49

Mottis, Y.-S

R The conjugation itself is catalyzed by glycine N-acyltransferase (GLYAT) in the mitochondrial matrix (for glycine) or by ACNAT enzymes for other amino acids

Nelson DB, Mehran RJ, Mitchell KG, Rajaram R, Correa AM, Bassett RL, Antonoff MB, Hofstetter WL, Roth JA, Sepesi B, Swisher SG, Walsh GL, Vaporciyan AA, Rice DC

Injectable routes typically provide more consistent systemic exposure and may be preferred for non-gastrointestinal applications requiring tissue delivery beyond the digestive tract