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Notably, RT-qPCR analysis showed a sharp increase in OCT4 mRNA expression, a marker of pluripotent stem cells and essential for TIC self-renewal [33], in the colonies formed in 3D gels relative to 2D culture conditions (Fig

et al., 2022)

This gas can be beneficial and protective, but like many things, excess levels can become toxic

But clinical testing doesn't support this assumption

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