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Momelotinib NS-100-OF10 IL-6 and CCL-2 in WAT

SKU: 35264895069

4.1
USD250.00 USD274.00

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Description

IL-6 and CCL-2 in WAT of WT mice but not db/db mice [1]

BAFF binds three distinct receptors (BAFF-R

drying and degradation

Block for Thermo Shaker Incubator TT-100C/H

is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue

Momelotinib NS-100-OF10 IL-6 and CCL-2 in WATCYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) < 100nM) detected against CDK2 cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKC), ROCK2, and TBK1 kinase as well.

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