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Cartilage or Joint Research Models In cartilage explant or defect models, the blend has been theorized to be evaluated for its potential to stimulate chondrocyte migration, ECM deposition (e.g., type II collagen, glycosaminoglycans), and integration into host tissue

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Inadequate use of vitamin B 12 , which may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia Pernicious anemia is the most common cause of vitamin B 12 deficiency