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Archived from the original on 30 December 2016

They may contain high-risk ingredients, such as prescription or controlled drugs, and additives or contaminants that may or may not be listed on the label

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The approaches work through different mechanisms and tissue concentrations

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)