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In simple terms, it means to bind something to an androgen receptor so that the androgen receptor is blocked off from binding with actual androgens, like testosterone or DHT
For vitamin B12 pills, most people take these daily in doses recommended by their doc but taking 1,000 mcg daily is pretty standard
In clinical trials, LGD-4033 significantly increased lean body mass without adverse androgenic effects, Basaria et al., Journal of the American Geriatrics Society

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