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Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance In Vitro and In Vivo

Mechanistic understanding doesn't automatically translate to clinical efficacy

Fe 2+ leaves the intestinal epithelial cells through the pathway mediated by FPN1 when the intracellular iron is too high ( 2+ is oxidized to Fe 3+ and tightly bound to transferrin (TF) at a ratio of 2:1

Accordingly, apolipoproteins (apoB and apoE) and apolipoprotein peptides have been used as LDL-receptor-mediated brain targeting ligands [26]

Disc-related back pain Intervertebral disc problems, including herniation, bulging, degeneration, and annular tears, cause some of the most challenging back pain conditions