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doi: 10.1007/s40279-016-0617-7, 82

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Additionally, the progression of some debilitating chronic diseases (eg, chronic kidney disease, endocrine diseases including diabetes and hypothyroidism, heart disease, osteoarthritis ) can be significantly reduced in dogs with early diagnosis and proper medical care

these genetic changes can be broadly characterized as causing defects in mucosal barrier function, immunoregulation or bacterial clearance

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