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Genes controlling cysteine metabolismsuch as those regulating transsulfuration pathwaysaffect glutathione precursor availability

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Further research is required to fully elucidate the specific oxidative modifications underlying AD pathology, the precise mechanisms of action of antioxidant therapies, and the strategies for optimizing these treatments for clinical application

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However, mean WL with GLP-1 RAs remains substantially lower than that achieved with BS and treatment response to GLP-1 RAs is heterogeneous