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In the presence of GSH, glutathione-S-transferase activity detoxifies xenobiotics and various physiological metabolites to form mercapturates and reactivated glucose-6-phosphate dehydrogenase [6]

doi: 10.1038/s12276-020-00504-8 88 LeoneRDZhaoLEnglertJMSunIMOhMHSunIHet al

Pesce et al suggested that such interaction enhances the immune response, fostering a more coordinated and effective defense against the infection and typically resulting in milder symptoms and mitigating the effects of the virus more effectively

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These pathways not only meet the energetic demands of immune activation and inflammation but also shape long-term gene expression through epigenetic mechanisms